Silicon oxycarbide glasses for blood-contact applications
Autor: | Carlo G. Pantano, Rui Zhuo, Erwin A. Vogler, Paolo Colombo |
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Rok vydání: | 2005 |
Předmět: |
Blood Platelets
Silicon Materials science Surface Properties Carbon Compounds Inorganic Biomedical Engineering chemistry.chemical_element Thermosetting polymer Biocompatible Materials Biochemistry Biomaterials Etching (microfabrication) Materials Testing Humans Organic chemistry Platelet activation Pyrolytic carbon Blood Coagulation Molecular Biology Cells Cultured General Medicine Platelet Activation Chemical engineering chemistry Glass Carbon Pyrolysis Stoichiometry Biotechnology |
Zdroj: | Acta Biomaterialia. 1:583-589 |
ISSN: | 1742-7061 |
Popis: | Silicon oxycarbide (SiOxCy) glass compositions are shown to exhibit a variable propensity to contact activate coagulation of whole human blood plasma that depends on X:Y surface stoichiometry. SiOxCy exhibit activation properties similar to pyrolytic carbon (PC) over a broad range of X:Y ratios. Surface composition of SiOxCy glass powders prepared by pyrolysis of thermosetting polysilsequioxanes roughly correlated with total carbon concentration of precursor resins and could be significantly modified by etching in alkaline solutions. Results suggest that SiOxCy may offer unique properties as a substitute for PC in medical-device applications demanding excellent tribological properties, such as artificial heart valves. |
Databáze: | OpenAIRE |
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