New Tests for Null Hypothesis of Non Unity Ratio of Proportions

Autor:	Kallappa M. Koti
Rok vydání:	2007
Předmět:	Pharmacology Statistics and Probability Models Statistical Restricted maximum likelihood Test procedures Research Design Sample size determination Data Interpretation Statistical Sample Size Likelihood-ratio test Binary data Statistics Confidence Intervals Humans Pharmacology (medical) Controlled Clinical Trials as Topic Null hypothesis Equivalence (measure theory) Random variable Mathematics
Zdroj:	Journal of Biopharmaceutical Statistics. 17:229-245
ISSN:	1520-5711 1054-3406
DOI:	10.1080/10543400601177426
Popis:	Testing for noninferiority and equivalence between an experimental therapy and a standard therapy in terms of the ratio of binomial proportions is considered. New tests based on the Fieller-Hinkley distribution of the ratio of random variables are proposed. Restricted maximum likelihood estimates of the null variances are used to derive the tests. Sample size determination is discussed. The proposed test procedure is extended to multiple tables. The tests are applied to numerical examples.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64bc89d05eacbdba58237bb37c6c6930 https://doi.org/10.1080/10543400601177426 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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