Amino acid composition of rat and human liver microsomes in normal and pathological conditions

Autor:	William Ferdinand, Gheorghe Benga
Rok vydání:	1995
Předmět:	Liver Cirrhosis Alanine Cholestasis Arginine Chemistry Biophysics Phenylalanine Cell Biology Cell Fractionation Biochemistry Rats Glycine Aspartic acid Microsomes Liver Animals Humans Amino Acids Leucine Threonine Tyrosine Molecular Biology
Zdroj:	Bioscience Reports. 15:111-116
ISSN:	1573-4935 0144-8463
DOI:	10.1007/bf01200145
Popis:	The amino acid composition of proteins from liver microsomes has been studied in rats and in human subjects with normal liver, with obstructive jaundice or liver cirrhosis. The pattern of the amino acid composition of microsomes appeared to be species-specific. Phenylalanine, threonine, serine, proline, histidine and [aspartic acid plus asparagine] were increased, while alanine, tyrosine, glycine and arginine were decreased in the human compared to the rat microsomes. In patients with obstructive jaundice of short duration (less than two months) only a slight decrease in leucine and phenylalanine could be noticed, while in the case of liver cirrhosis amino acid composition was markedly changed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64a9bdc84dc06826425094120618180f https://doi.org/10.1007/bf01200145 Zobrazit plný text záznamu Full text from SpringerLink