Long-term follow-up of high-dose treatment with autologous haematopoietic progenitor cell support in 693 patients with follicular lymphoma: an EBMT registry study

Autor:	Shimon Slavin, Christian Gisselbrecht, G. Taghipour, L. Fouillard, Anna Sureda, N. Schmitz, H. Tilly, Silvia Montoto, Carmen Canals, Christophe Fruchart, T. A. Lister, Ama Z. S. Rohatiner, Augustin Ferrant, Veronique Leblond, Corinne Haioun, Eulogio Conde, Noel-Jean Milpied, Anthony H. Goldstone
Rok vydání:	2007
Předmět:	Adult Male Oncology Cancer Research medicine.medical_specialty Adolescent Follicular lymphoma Bone Marrow Cells Transplantation Autologous Disease-Free Survival Internal medicine medicine Humans Registries Progenitor cell Lymphoma Follicular Bone Marrow Transplantation Hematology business.industry Stem Cells Remission Induction Secondary Myelodysplastic Syndrome Middle Aged Hematopoietic Stem Cells medicine.disease Surgery Lymphoma Regimen Haematopoiesis Leukemia Treatment Outcome Female business
Zdroj:	Leukemia. 21:2324-2331
ISSN:	1476-5551 0887-6924
Popis:	To evaluate the outcome of a large series of patients who received high-dose treatment (HDT) for follicular lymphoma (FL), 693 patients undergoing HDT (total-body irradiation (TBI)-containing regimen: 58%; autologous bone marrow (BM)/peripheral blood progenitor cells (PBPCs): 378/285 patients) were included in the study. A total of 375 patients (54%) developed recurrent lymphoma, 10-year progression-free survival (PFS) being 31%. On multivariate analysis, younger age (P=0.003) and HDT in first complete remission (CR1) (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64a877da53a6d0574b674e79c273b306 https://doi.org/10.1038/sj.leu.2404850 Zobrazit plný text záznamu Plný text ve formátu PDF