Datasets for 'Filling of a water-free void explains the allosteric regulation of the β1-adrenergic receptor by cholesterol'
| Autor: | Abiko, Layara Akemi, Dias Teixeira, Raphael, Engilberge, Sylvain, Grahl, Anne, Mühlethaler, Tobias, Sharpe, Timothy, Grzesiek, Stephan |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| DOI: | 10.5281/zenodo.4926012 |
| Popis: | Raw data for the X-ray structure determination of a xenon-derivatized isoprenaline∙β1AR crystal, the xenon atom anomalous maps, NMR spectra, and for the ITC curves presented in the manuscript "Filling of a water-free void explains the allosteric regulation of the β1-adrenergic receptor by cholesterol". The main folder (Xe_isoprenaline_b1AR) contains two subfolders. The coordinate file (.pdb), the hkl file, and the electron density map (.mtz) are placed in the folder "structure". The second folder, “anomalous_map”, contains the anomalous maps (.pha and .map), and the hkl files for the four different crystals evaluated (organized in separate folders for the each crystal 1-4). The images for the 4 crystals are placed in separate folders (images_crystal_1, images_crystal_2, images_crystal_3, and images_crystal_4). The folder “NMR” contains processed 1H-15N TROSY NMR spectra (.DAT files), and full Bruker directories for 1H experiments. The datasets are organized in subfolders named according to the manuscript figures. The folder “ITC” contains the original ITC files (.itc) presented in Figure 4 and supplementary Figure S5 of the manuscript. This work was supported by the Swiss National Science Foundation (Grants CRSK-3_195592 to L.A.A., and 31-149927, 31-173089, 31-201270 to S.G.). |
| Databáze: | OpenAIRE |
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