Differences in health-related quality of life scores after orthotopic liver transplantation with respect to selected socioeconomic factors
| Autor: | Steven Han, Sammy Saab, Ronald W. Busuttil, Hillary Bownik, Johnny C. Hong, Noel Ayoub, Francisco Durazo, Douglas G. Farmer, Zobair M. Younossi |
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| Rok vydání: | 2011 |
| Předmět: |
Gerontology
Adult Male medicine.medical_specialty medicine.medical_treatment Psychological intervention Liver transplantation Chronic liver disease Sex Factors Quality of life Bayesian multivariate linear regression Surveys and Questionnaires medicine Ethnicity Humans Socioeconomic status Aged Transplantation Insurance Health Hepatology business.industry Health Status Disparities Middle Aged medicine.disease Preferred provider organization Mental health Liver Transplantation surgical procedures operative Socioeconomic Factors Physical therapy Quality of Life Regression Analysis Surgery Female business |
| Zdroj: | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 17(5) |
| ISSN: | 1527-6473 |
| Popis: | One of the current ultimate goals of orthotopic liver transplantation (OLT) is the improvement of patients' health-related quality of life (HRQOL). The purpose of this study was to look at the effects of socioeconomic and demographic differences on the short-term and long-term HRQOL outcomes of OLT recipients. Three hundred three adult OLT recipients who were seen at the University of California Los Angeles were administered the Medical Outcomes Study Short Form 36 (SF-36), the Chronic Liver Disease Questionnaire (CLDQ), and a demographic survey. A parsimonious model of 12 socioeconomic and demographic predictors was identified. Their simultaneous influence on each SF-36 and CLDQ HRQOL domain score was evaluated with multivariate linear regression and backward selection. Hepatitis C virus impaired HRQOL; this was shown in the SF-36 Vitality and Bodily Pain domains and in most CLDQ domains. Females experienced more HRQOL impairment only within the CLDQ Abdominal Symptoms domain. OLT recipients who were married had better SF-36 Role–Emotion domain scores. OLT recipients with more than 12 years of education had better SF-36 Physical Functioning scores. Employed OLT recipients had less HRQOL impairment; this was evidenced by better scores in multiple domains of the SF-36 and the CLDQ. OLT patients with health maintenance organization or preferred provider organization insurance had higher HRQOL scores within almost all SF-36 and CLDQ domains. Patients with a mix of public and private insurance had significantly higher HRQOL scores in comparison with those with only public insurance. Identifying patients at higher risk for worse HRQOL scores, less satisfaction with OLT results, and greater problems with fatigue or mental health stressors will assist transplant centers in using their medical teams to develop early interventions and multidisciplinary approaches to improve HRQOL outcomes after OLT. Liver Transpl 17:580–590, 2011. © 2011 AASLD. |
| Databáze: | OpenAIRE |
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