Distribution of NADPH-diaphorase-positive neurons in the enteric nervous system of the human colon
Autor: | Wolfgang Kühnel, Heinz-Jürgen Krammer, Ming Zhang |
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Rok vydání: | 1994 |
Předmět: |
Neurons
Pathology medicine.medical_specialty Plexus Colon NADPH Dehydrogenase Myenteric Plexus Muscle Smooth General Medicine Anatomy Biology Staining Nerve Fibers medicine.anatomical_structure medicine Humans Immunohistochemistry Distribution (pharmacology) Enteric nervous system Neuron Myenteric plexus Human colon Developmental Biology |
Zdroj: | Annals of Anatomy - Anatomischer Anzeiger. 176:137-141 |
ISSN: | 0940-9602 |
Popis: | Recent investigations have demonstrated the colonization of NOS-immunoreactivity and NADPH-diaphorase staining in central and peripheral neurons. The current study investigates the presence and distribution of NADPH-diaphorase-stained nerve cells and fibres in whole-mount preparations of the enteric nervous system of the human colon. Numerous NADPH-diaphorase-stained nerve cell bodies were found in the plexus myentericus and in the plexus submucosus externus. In contrast, we found but very few NADPH-diaphorase-stained nerve cells in the plexus submucosus internus. The majority of the NADPH-diaphorase-stained nerve cells had morphological characteristics similar to those of the Dogiel type I neuron, i.e. possessing broad flat dendrites and one major axonal projection. NADPH-diaphorase-stained nerve fibres can be observed in all three ganglionic networks and in the aganglionic plexus of the circular muscle layer. |
Databáze: | OpenAIRE |
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