Assessment of macular choroidal thickness, central macular thickness and retinal nerve fiber layer in patients receiving oral isotretinoin treatment
| Autor: | Serap Ozturk Durur, Metin Dastan, Murat Kocamaz, Onur Karadag |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty genetic structures Adolescent Nerve fiber layer Nerve fibre layer Administration Oral Toxicology Retina chemistry.chemical_compound Young Adult Nerve Fibers Optical coherence tomography Ophthalmology Acne Vulgaris Medicine Humans In patient skin and connective tissue diseases Isotretinoin medicine.diagnostic_test business.industry Choroid Retinal General Medicine Oral isotretinoin eye diseases medicine.anatomical_structure chemistry Female sense organs Dermatologic Agents business Tomography Optical Coherence Coherence (physics) |
| Zdroj: | Cutaneous and ocular toxicology. 39(3) |
| ISSN: | 1556-9535 |
| Popis: | To investigate the impact of oral isotretinoin therapy in choroidal thickness, central macular thickness (CMT), and retinal nerve fibre layer (RNFL) thickness using optical coherence tomography (OCT).Choroidal thicknesses, CMT, and RNFL thickness of 64 eyes were evaluated at baseline and the end of the third month of isotretinoin therapy by spectral-domain OCT. For assessment of choroidal thickness, OCT measurements were obtained at the fovea with 6 additional measurements at adjacent locations (at 500-1000-1500 µm temporal to the fovea and 500-1000-1500 µm nasal to the fovea).There was not a statistically significant difference between the baseline and third-month follow-up measurements of choroidal thicknesses at seven distinct locations (After the use of oral isotretinoin for 3 months, no significant side effects have been observed in choroidal thickness, CMT, and RNFL thickness by OCT. |
| Databáze: | OpenAIRE |
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