Eight-day Inpatient Directly Observed Therapy for Antiretroviral Therapy (ART) Failure: A Tool For Preventing Unnecessary ART Changes and Optimizing Adherence Support

Autor:	Yolanda Mejia, Robin Dewar, Safia S Kuriakose, Frank Maldarelli, Alice K. Pau, H. Clifford Lane, Nicole E Winchester, Nicola Dee, Elizabeth Laidlaw, Pamela Stoll, Michael A. Proschan
Rok vydání:	2019
Předmět:	0301 basic medicine Microbiology (medical) medicine.medical_specialty Anti-HIV Agents Human immunodeficiency virus (HIV) HIV Infections Antiretroviral drug Drug resistance medicine.disease_cause Medication Adherence 03 medical and health sciences 0302 clinical medicine Antiretroviral Therapy Highly Active Internal medicine Drug Resistance Viral medicine Humans Treatment Failure 030212 general & internal medicine Directly Observed Therapy Inpatients business.industry Viral Load 030112 virology Antiretroviral therapy VIROLOGIC FAILURE Regimen Infectious Diseases HIV-1 Brief Reports business
Zdroj:	Clin Infect Dis
ISSN:	1537-6591 1058-4838
DOI:	10.1093/cid/ciz590
Popis:	Eight-day inpatient directly observed therapy confirmed nonadherence as the major cause of virologic failure for 9 (45%) of 20 highly treatment-experienced persons with human immunodeficiency virus, extensive antiretroviral drug resistance, and high self-reported adherence rates, preventing unnecessary regimen changes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6492ec9d0d13572339216c6d163de26c https://doi.org/10.1093/cid/ciz590 Zobrazit plný text záznamu