Simultaneous use of phenylboronic acid as a phase transfer agent and targeting ligand for gold nanoparticles
| Autor: | Zehra Karaagac, Ismail Ocsoy, Nilay Ildiz, Irem Onal |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
inorganic chemicals
Materials science Aqueous solution Ligand Mechanical Engineering Diol food and beverages 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics 01 natural sciences Combinatorial chemistry 0104 chemical sciences chemistry.chemical_compound Membrane Molecular recognition chemistry Transfer agent Mechanics of Materials Colloidal gold General Materials Science Phenylboronic acid 0210 nano-technology |
| Popis: | Herein, we have rationally utilized 4-mercaptophenylboronic acid (4-MPBA) as a hydrophilic ligand for phase transfer of gold (Au) NPs from non-hydrolytic system into aqueous solutions and as a targeting ligand for recognition of model pathogen. In principle, while free thiol end of 4-MPBA conjugates to surface of hydrophobic Au NPs to form stable Au NP in aqueous solutions, diol groups can bind to glycan on the membrane of pathogens through cis-diol configuration. Finally, this ligand can be applied to other hydrophobic metallic and metel oxide NPs for phase transfer and molecular recognition. (C) 2020 Elsevier B.V. All rights reserved. |
| Databáze: | OpenAIRE |
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