Assignments of the tyrosinase related protein-1 and -2 genes to human chromosome bands 9p23 and 13q32.1 by in situ hybridization
| Autor: | Eunpyo Moon, Mahn Joon Ha, Young-Mi Lee, Wankee Kim, Hyon Ju Kim, Sungbin Im, Min Sook Ryu |
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| Rok vydání: | 2000 |
| Předmět: |
Genetics
Bacterial artificial chromosome Membrane Glycoproteins medicine.diagnostic_test Chromosomes Human Pair 13 Tyrosinase Chromosome Proteins General Medicine In situ hybridization Biology Molecular biology Intramolecular Oxidoreductases medicine Humans Genomic library Chromosomes Human Pair 9 Oxidoreductases Chromosome 22 Gene In Situ Hybridization Fluorescence Fluorescence in situ hybridization Gene Library |
| Zdroj: | Yonsei medical journal. 41(3) |
| ISSN: | 0513-5796 |
| Popis: | To determine the precise chromosomal localization of tyrosine related protein-1 and -2 (TRP-1 and TRP-2) genes by fluorescence in situ hybridization, we used DNAs isolated from human bacterial artificial chromosome clones. They contain genomic sequences with approximately 120 kb inserts for TRP-1 and TRP-2. The TRP-1 and TRP-2 genes were assigned to human chromosome bands 9p23 and 13q32.1, respectively. These results confirmed the previously mapped location for the TRP-1 gene and more precisely located the TRP-2 gene, which had previously been mapped to chromosome 13q31-q32. |
| Databáze: | OpenAIRE |
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