Regenerative Medicine: lessons from Mother Nature
| Autor: | Michelle E. Scarritt, Crisanto M. Torres, Luai Huleihel, Stephen F. Badylak, Anjani K. Ravindra, Juan Diego Naranjo |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Embryology Tissue Engineering Regeneration (biology) Biomedical Engineering Anatomy Biology Regenerative Medicine Regenerative medicine 03 medical and health sciences 030104 developmental biology Tissue engineering Animals Humans Stem cell Stem cell biology Developmental biology Neuroscience Blastema Special Report Ex vivo Developmental Biology |
| Zdroj: | Regenerative medicine. 11(8) |
| ISSN: | 1746-076X |
| Popis: | Regenerative medicine strategies for the restoration of functional tissue have evolved from the concept of ex vivo creation of engineered tissue toward the broader concept of in vivo induction of functional tissue reconstruction. Multidisciplinary approaches are being investigated to achieve this goal using evolutionarily conserved principles of stem cell biology, developmental biology and immunology, current methods of engineering and medicine. This evolution from ex vivo tissue engineering to the manipulation of fundamental in vivo tenets of development and regeneration has the potential to capitalize upon the incredibly complex and only partially understood ability of cells to adapt, proliferate, self-organize and differentiate into functional tissue. |
| Databáze: | OpenAIRE |
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