Correlates of drug use cessation among participants in the Canadian HIV–HCV Co-infection Cohort
| Autor: | Sahar Saeed, Mark W. Tyndall, Erica E. M. Moodie, Lina Hu, Emilie Maurais, Martin Potter, Joseph Cox, Curtis Cooper, Kathleen Rollet, Mark Hull, John Gill, Marina B. Klein, Nikki Bozinoff, Stephanie Law |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Drug Canada medicine.medical_specialty Substance-Related Disorders media_common.quotation_subject Population HIV Infections Toxicology Logistic regression Cohort Studies Risk Factors Humans Medicine Pharmacology (medical) Prospective Studies Social determinants of health education Psychiatry media_common Pharmacology education.field_of_study Coinfection business.industry Addiction Odds ratio Middle Aged Hepatitis C Confidence interval Psychiatry and Mental health Cohort Patient Compliance Female Substance Abuse Treatment Centers business Follow-Up Studies Demography |
| Zdroj: | Drug and Alcohol Dependence. 137:121-128 |
| ISSN: | 0376-8716 |
| Popis: | Background Ongoing drug use remains a barrier to HIV and HCV treatment. We examined the occurrence and correlates of drug use cessation among HIV–HCV co-infected drug users participating in HIV care. Methods Participants from the Canadian Co-infection Cohort reporting drug use (injecting drugs and/or smoking crack) with at least two follow-up visits were included ( n = 521 (43%), 1832 visits). Socio-demographics, behavioural, and health information were collected at each six-month visit. Associations with cessation (no drug use since last visit) were examined using non-linear mixed effects logistic regression models with random intercepts. Results During follow-up, 361 (69%) participants ceased using drugs. Having a fixed address (aOR [adjusted odds ratio] 1.73, CI [95% confidence interval] 1.02–2.96) and smoking crack without injecting drugs (aOR 3.10, CI 2.05–4.71) were positively associated. Living alone (aOR 0.47, CI 0.35–0.63), current tobacco use (aOR 0.41, CI 0.26–0.64), hazardous alcohol drinking (aOR 0.67, CI 0.49–0.91), snorting drugs (aOR 0.52, CI 0.37–0.74), having a greater exposure to addiction programmes (aOR 0.88, CI 0.81–0.94), having been recruited in Quebec or Nova Scotia (aOR 0.41, CI 0.25–0.66), and British Columbia or Alberta (aOR 0.51, CI 0.32–0.82) were negatively associated. Various socio-demographic (age, education) and health-related (HIV duration, care adherence) factors were not associated. Conclusion Drug use cessation among HIV–HCV co-infected persons is relatively common in this cohort. Stable housing and supportive living situations seem to be important facilitators for drug use cessation in this population. Greater efforts should be made to retain patients in addiction treatment programmes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect