Hairy Root Cultures—A Versatile Tool With Multiple Applications
| Autor: | Marina Guillet, Kirsi Marja Oksman-Caldentey, Suvi T. Häkkinen, Florian Cardon, Camille Lemasson, Anneli Ritala, Noemi Gutierrez-Valdes |
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| Rok vydání: | 2020 |
| Předmět: |
0106 biological sciences
Root (linguistics) Agrobacterium media_common.quotation_subject Review molecular farming Plant Science lcsh:Plant culture recombinant proteins 01 natural sciences Adaptability 03 medical and health sciences lcsh:SB1-1110 030304 developmental biology media_common 2. Zero hunger 0303 health sciences biology specialized metabolites Rhizobium rhizogenes Multiple applications food and beverages biology.organism_classification Agrobacterium rhizogenes hairy roots Biochemical engineering 010606 plant biology & botany |
| Zdroj: | Frontiers in Plant Science, Vol 11 (2020) Frontiers in Plant Science Gutierrez-Valdes, N, Häkkinen, S T, Lemasson, C, Guillet, M, Oksman-Caldentey, K M, Ritala, A & Cardon, F 2020, ' Hairy Root Cultures—A Versatile Tool With Multiple Applications ', Frontiers in Plant Science, vol. 11, 33 . https://doi.org/10.3389/fpls.2020.00033 |
| ISSN: | 1664-462X |
| DOI: | 10.3389/fpls.2020.00033 |
| Popis: | Hairy roots derived from the infection of a plant by Rhizobium rhizogenes (previously referred to as Agrobacterium rhizogenes) bacteria, can be obtained from a wide variety of plants and allow the production of highly diverse molecules. Hairy roots are able to produce and secrete complex active glycoproteins from a large spectrum of organisms. They are also adequate to express plant natural biosynthesis pathways required to produce specialized metabolites and can benefit from the new genetic tools available to facilitate an optimized production of tailor-made molecules. This adaptability has positioned hairy root platforms as major biotechnological tools. Researchers and industries have contributed to their advancement, which represents new alternatives from classical systems to produce complex molecules. Now these expression systems are ready to be used by different industries like pharmaceutical, cosmetics, and food sectors due to the development of fully controlled large-scale bioreactors. This review aims to describe the evolution of hairy root generation and culture methods and to highlight the possibilities offered by hairy roots in terms of feasibility and perspectives. |
| Databáze: | OpenAIRE |
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