Chromium-catalysed efficient N-formylation of amines with a recyclable polyoxometalate-supported green catalyst

Autor:	Dan Demin, Sheng Han, Yongge Wei, Fubo Chen, Whenshu Zhao, Han Yu
Rok vydání:	2021
Předmět:	inorganic chemicals Inorganic Chemistry chemistry.chemical_compound Chromium Chemistry Formic acid Polyoxometalate chemistry.chemical_element Chemoselectivity Combinatorial chemistry Formylation Catalysis
Zdroj:	Dalton Transactions. 50:90-94
ISSN:	1477-9234 1477-9226
DOI:	10.1039/d0dt03300f
Popis:	A simple and efficient protocol for the formylation of amines with formic acid, catalyzed by a polyoxometalate-based chromium catalyst, is described. Notably, this method shows excellent activity and chemoselectivity for the formylation of primary amines; diamines have also been successfully employed. Importantly, the chromium catalyst is potentially non-toxic, environmentally benign and safer than the widely used high valence chromium catalysts such as CrO3 and K2Cr2O7. The catalyst can be recycled several times with a negligible impact on activity. Finally, a plausible mechanism is provided based on the observation of intermediate and control experiments.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6481c255b9ea94c24a274174682f9c8e https://doi.org/10.1039/d0dt03300f Zobrazit plný text záznamu