Endometrial adenocarcinoma presenting as a suprasellar mass: lessons to be learned
Autor: | Franco M. Muggia, Julia Fehniger, Evgenia Granina, Joshua S. Silverman, Andrea Downey, Douglas Kondziolka, Dimitris G. Placantonakis |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
Cancer Research
medicine.medical_specialty endocrine system diseases stage IA cancer panhypopituitarism Optic chiasm Case Report 03 medical and health sciences 0302 clinical medicine Biopsy Medicine metastases Bitemporal hemianopsia Pituitary stalk 030219 obstetrics & reproductive medicine adenocarcinoma medicine.diagnostic_test business.industry Endometrial cancer radiosurgery medicine.disease Metastatic Endometrial Adenocarcinoma HER2/neu Serous fluid medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis Adenocarcinoma Radiology business |
Zdroj: | ecancermedicalscience |
ISSN: | 1754-6605 |
Popis: | A 66-year-old woman with a history of stage IA mixed endometrioid and serous endometrial cancer presented to our centre with 2 weeks of worsening headaches nearly 4 years after her initial surgery. At admission, she manifested bitemporal hemianopsia, difficulty walking and clinical and laboratory findings of panhypopituitarism, including diabetes insipidus. Magnetic resonance imaging of the brain revealed a 2.7 cm sellar/suprasellar mass compressing the optic chiasm and infiltrating the pituitary stalk. Computerised tomography documented mediastinal, lung, adrenal and liver involvement, including a 2.5 cm palpable left supraclavicular node that on excisional biopsy demonstrated metastatic endometrial adenocarcinoma. Due to the advanced stage of her cancer as well as the presence of multiple metastases, including lung and hepatic metastases causing post-obstructive pneumonia and coagulopathy, the sellar/suprasellar mass was treated with fractionated radiosurgery rather than surgical excision. |
Databáze: | OpenAIRE |
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