Silicone wristbands compared with traditional polycyclic aromatic hydrocarbon exposure assessment methods

Autor: Julie B. Herbstman, Katrina M. Waters, Kim A. Anderson, David Camann, Laurel Kincl, Richard P. Scott, Darrell Holmes, Lehyla Calero, Holly M. Dixon, Antonia M. Calafat
Rok vydání: 2018
Předmět:
Personal monitoring
Silicones
Polycyclic aromatic hydrocarbon
Air Pollutants
Occupational
010501 environmental sciences
030501 epidemiology
01 natural sciences
Biochemistry
Analytical Chemistry
Cohort Studies
03 medical and health sciences
Air monitoring
chemistry.chemical_compound
Silicone
Limit of Detection
Pregnancy
Occupational Exposure
Biomonitoring
polycyclic compounds
Humans
Polycyclic Aromatic Hydrocarbons
Environmental toxicology
Paper in Forefront
0105 earth and related environmental sciences
Exposure assessment
chemistry.chemical_classification
Active sampling
Pah exposure
3. Good health
Exposome
Passive sampling
chemistry
Maternal Exposure
13. Climate action
Environmental chemistry
Assessment methods
Environmental science
Female
0305 other medical science
Birth cohort
Biomarkers
Environmental Monitoring
Zdroj: Analytical and Bioanalytical Chemistry
ISSN: 1618-2650
1618-2642
DOI: 10.1007/s00216-018-0992-z
Popis: Currently there is a lack of inexpensive, easy-to-use technology to evaluate human exposure to environmental chemicals, including polycyclic aromatic hydrocarbons (PAHs). This is the first study in which silicone wristbands were deployed alongside two traditional personal PAH exposure assessment methods: active air monitoring with samplers (i.e., polyurethane foam (PUF) and filter) housed in backpacks, and biological sampling with urine. We demonstrate that wristbands worn for 48 h in a non-occupational setting recover semivolatile PAHs, and we compare levels of PAHs in wristbands to PAHs in PUFs-filters and to hydroxy-PAH (OH-PAH) biomarkers in urine. We deployed all samplers simultaneously for 48 h on 22 pregnant women in an established urban birth cohort. Each woman provided one spot urine sample at the end of the 48-h period. Wristbands recovered PAHs with similar detection frequencies to PUFs-filters. Of the 62 PAHs tested for in the 22 wristbands, 51 PAHs were detected in at least one wristband. In this cohort of pregnant women, we found more significant correlations between OH-PAHs and PAHs in wristbands than between OH-PAHs and PAHs in PUFs-filters. Only two comparisons between PAHs in PUFs-filters and OH-PAHs correlated significantly (rs = 0.53 and p = 0.01; rs = 0.44 and p = 0.04), whereas six comparisons between PAHs in wristbands and OH-PAHs correlated significantly (rs = 0.44 to 0.76 and p = 0.04 to
Databáze: OpenAIRE
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