Clinical and imaging features of carcinosarcoma of the uterus and cervix
| Autor: | Kangkang Xue, Jianbo Gao, Wenpeng Huang, Liming Li, Yi-Jing Han, Lei-yu Feng, Rui Wang |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
R895-920 Cervix Medical physics. Medical radiology. Nuclear medicine Magnetic resonance imaging Carcinosarcoma Diagnosis medicine Radiology Nuclear Medicine and imaging Vaginal bleeding Neuroradiology Tomography (X-ray computed) medicine.diagnostic_test business.industry Uterine carcinosarcoma Ultrasound Interventional radiology medicine.disease medicine.anatomical_structure Cervical Carcinosarcoma Original Article Radiology medicine.symptom business |
| Zdroj: | Insights into Imaging Insights into Imaging, Vol 12, Iss 1, Pp 1-10 (2021) |
| ISSN: | 1869-4101 |
| Popis: | Aim The purpose of our study was to analyze the clinical and imaging features of uterine carcinosarcoma (UCS) and cervical carcinosarcoma (CCS), and to explore the diagnostic and staging accuracy of computed tomography (CT) and magnetic resonance imaging (MRI) examinations. Methods 41 patients including 37 with UCS and 4 with CCS from July 2011 to September 2020 were enrolled in the study. Of the 37 UCS cases, 7 had CT images, 27 had MRI images, and 3 had both CT and MRI images. The Clinical data, CT or MRI imaging findings were analyzed. Diagnosis and staging accuracy of CT and MRI images were also analyzed. Results Carcinosarcoma usually occurs in postmenopausal women (40/41), with the typical clinical symptom being vaginal bleeding (33/41). The CA125 degree was significantly different between the two invasion depth groups (p = 0.011). Most uterine carcinosarcomas showed unclear boundaries, uneven density, low or equal signal on T1WI, high or mixed signal on T2WI, uneven high signal on diffusion-weighted image (DWI), and mild enhancement. The diagnostic accuracies of CT and MRI for carcinosarcoma were 0% and 3.33%, respectively. The diagnostic accuracy for malignant tumors on CT and MRI was 50% and 83.33%, respectively. Conclusions Carcinosarcoma lesions presented with huge mass filling in the cavity, and some presented with small polypoid lesions or endometrial thickening. Evaluation of lymph node metastasis is a significant challenge for imaging staging. |
| Databáze: | OpenAIRE |
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