Clinical characteristics and outcomes of patients admitted with acute heart failure: insights from a single-center heart failure registry in South India
| Autor: | Vidhyakar Balasubramaniam, Rajendiran Gopalan, Arun Kaushik Ponnusamy, Aashiq Ahamed Shukkoor, Ramasamy Palanimuthu, Premkrishna Anandan, Tamilarasu Kaliappan, Vinoth Doraiswamy, Nimmy Elizabeth George, Sivakumar Velusamy, Shanmugasundaram Radhakrishnan |
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| Rok vydání: | 2021 |
| Předmět: |
Univariate analysis
medicine.medical_specialty Registry Ejection fraction business.industry Renal function Mean age Heart failure 030204 cardiovascular system & hematology Mortalities medicine.disease Single Center 03 medical and health sciences 0302 clinical medicine In-hospital Internal medicine RC666-701 Epidemiology Cohort medicine Diseases of the circulatory (Cardiovascular) system 030212 general & internal medicine business |
| Zdroj: | The Egyptian Heart Journal, Vol 73, Iss 1, Pp 1-10 (2021) |
| ISSN: | 2090-911X |
| Popis: | Background The epidemiology of HF in India is largely unexplored. Current resources are based on a few hospital-based and a community-based registry from North India. Thus, we present the data from a single hospital-based registry in South India. Patients admitted with acute heart failure over a period of 1 year were enrolled in the registry and were characterized based on their ejection fraction (EF) measured by echocardiogram. The clinical profile of the patients was assessed, including their in-hospital outcomes. One-way ANOVA and univariate analysis were performed for comparison between three EF-based groups and for the assessment of in-hospital outcomes. Results A total of 449 patients were enrolled in the registry, of which 296, 90, and 63 patients were categorized as, HFrEF, HFmrEF, and HFpEF, respectively. The prevalence of HFrEF was higher (65.99%). The mean age (SD) of the study cohort was 59.9±13.3. The majority of the patients presented with acute denovo HF (67%) and were more likely to be males (65.9%). The majority of patients presented with warm and wet clinical phenotype (86.4%). In hospital mortality was higher in HFmrEF (3.3%). Conclusion Patients with HFrEF had high adherence to guideline-directed medical therapy (GDMT). HFrEF patients were also likely to have longer hospital stay along with a worsening of renal function. The in-hospital mortality was comparable between the EF-based groups. Additionally, the association of clinical phenotypes with outcome highlighted that patients in warm and wet phenotype had a longer length of hospital stay, whereas the mortality and worsening renal function rates were found to be significantly higher in the cold and wet group. |
| Databáze: | OpenAIRE |
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