Near-infrared spectroscopy muscle oximetry of patients with postural orthostatic tachycardia syndrome
| Autor: | Harry T. Whelan, Mahsa Ranji, Shima Mehrvar, Jeffrey J. Sugar, Gisela Chelimsky, Brendan J. Quirk, Thomas C. Chelimsky, Parvathi Kadamati |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Tachycardia
medicine.medical_specialty Biomedical Engineering Medicine (miscellaneous) Orthostatic intolerance Blood volume 030204 cardiovascular system & hematology lcsh:Technology Article 03 medical and health sciences 0302 clinical medicine Internal medicine Postural Orthostatic Tachycardia Syndrome Medicine lcsh:QC350-467 Hemoglobin business.industry lcsh:T technology industry and agriculture Oxygenation medicine.disease head-up tilt table Atomic and Molecular Physics and Optics Electronic Optical and Magnetic Materials Blood pressure blood volume Blood oxygenation Cardiology oxygenation medicine.symptom business 030217 neurology & neurosurgery lcsh:Optics. Light |
| Zdroj: | Journal of innovative optical health sciences Journal of Innovative Optical Health Sciences, Vol 11, Iss 5, Pp 1850026-1-1850026-9 (2018) |
| ISSN: | 1793-5458 |
| Popis: | Postural orthostatic tachycardia syndrome (POTS) is a disabling condition characterized by orthostatic intolerance with tachycardia in the absence of drop-in blood pressure. A custom-built near-infrared spectroscopy device (NIRS) is applied to monitor the muscle oxygenation, noninvasively in patients undergoing incremental head-up tilt table (HUT). Subjects (6 POTS patients and 6 healthy controls) underwent 30[Formula: see text]mins of 70∘ on a HUT. The results showed a significant difference in deoxyhemoglobin (Hb), change-in-oxygenation [Formula: see text] and blood volume [Formula: see text] between patients and healthy controls. However, oxyhemoglobin (HbO2) showed a significantly faster rate of change in the healthy controls during the first 10[Formula: see text]mins of the tilt and during the recovery. This NIRS muscle oximetry tool provides quantitative measurements of blood oxygenation monitoring in diseases such as POTS. |
| Databáze: | OpenAIRE |
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