Case Presentation: Xenograft Resistance to Protease Degradation in a Vasculitic Ulcer
| Autor: | Gerit Mulder, Daniel K. Lee |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Male
Vasculitis medicine.medical_specialty Pathology medicine.medical_treatment Transplantation Heterologous Vasculitic Ulcer Inflammation Gastroenterology Internal medicine medicine Humans Foot Ulcer Autoimmune disease Wound Healing Protease business.industry Graft Survival General Medicine Middle Aged medicine.disease Cryoglobulinemia Debridement Rheumatoid arthritis Etiology Surgery medicine.symptom business Follow-Up Studies Peptide Hydrolases |
| Zdroj: | The International Journal of Lower Extremity Wounds. 8:157-161 |
| ISSN: | 1552-6941 1534-7346 |
| DOI: | 10.1177/1534734609344126 |
| Popis: | Vasculitic ulcers are related to numerous underlying etiologies including autoimmune disease, rheumatoid arthritis and other inflammatory conditions.The resulting ulcerations are associated with high levels of pain, inflammation and tissue necrosis. Current therapies, including surgical intervention, are limited by the underlying inflammatory process and complications secondary to the wound etiology. conservative care has been relatively unsuccessful in promoting wound closure.This case presentations reviews the successful results of using a xenograft in the treatment of an inflammatory ulcer associated with cryoglobulinemia and vasculitis. Product integrity was maintained postoperatively, compared to an allograft, thereby allowing the wound treatment site to progress to closure.The type of cross linkage of acellular grafts may have a direct effect on product stability and treatment outcomes. |
| Databáze: | OpenAIRE |
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