Percutaneous double lumen cannula for right ventricle assist device system: A computational fluid dynamics study

Autor: Francesca Condemi, Guangfeng Zhao, Dongfang Wang, Joseph B. Zwischenberger, Cherry Ballard-Croft, Gionata Fragomeni, Fuqian Yang, Cameron Jones
Rok vydání: 2016
Předmět:
Zdroj: Biocybernetics and Biomedical Engineering. 36:482-490
ISSN: 0208-5216
DOI: 10.1016/j.bbe.2016.04.002
Popis: Our goal is to develop a double lumen cannula (DLC) for a percutaneous right ventricular assist device (pRVAD) in order to eliminate two open chest surgeries for RVAD installation and removal. The objective of this study was to evaluate the performance, flow pattern, blood hemolysis, and thrombosis potential of the pRVAD DLC.Computational fluid dynamics (CFD), using the finite volume method, was performed on the pRVAD DLC. For Reynolds numbers4000, the laminar model was used to describe the blood flow behavior, while shear-stress transport k-ω model was used for Reynolds numbers4000. Bench testing with a 27 Fr prototype was performed to validate the CFD calculations.There was1.3% difference between the CFD and experimental pressure drop results. The Lagrangian approach revealed a low index of hemolysis (0.012% in drainage lumen and 0.0073% in infusion lumen) at 5 l/min flow rate. Blood stagnancy and recirculation regions were found in the CFD analysis, indicating a potential risk for thrombosis.The pRVAD DLC can handle up to 5 l/min flow with limited potential hemolysis. Further modification of the pRVAD DLC is needed to address blood stagnancy and recirculation.
Databáze: OpenAIRE
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