Endomyocardial fibrosis and myocardial infarction leading to diastolic and systolic dysfunction requiring transplantation
| Autor: | De Gaspari, M., Toscano, G., Bagozzi, L., Metra, M., Lombardi, C., Rizzo, S., Angelini, A., Perazzolo Marra, M., Gerosa, G., Basso, C., Angelini, Annalisa |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Endomyocardial biopsy Endomyocardial fibrosis Heart transplantation Ischemic heart disease 2734 Cardiology and Cardiovascular Medicine 0301 basic medicine medicine.medical_specialty animal structures Systole Biopsy medicine.medical_treatment Myocardial Infarction Diastole 030204 cardiovascular system & hematology Ventricular Function Left Pathology and Forensic Medicine Coronary artery disease Ventricular Dysfunction Left 03 medical and health sciences 0302 clinical medicine Internal medicine Humans Medicine Myocardial infarction Heart Failure business.industry General Medicine medicine.disease Magnetic Resonance Imaging Thrombosis Transplantation Treatment Outcome 030104 developmental biology Heart failure Cardiology business |
| Zdroj: | Cardiovascular Pathology. 38:21-24 |
| ISSN: | 1054-8807 |
| DOI: | 10.1016/j.carpath.2018.10.010 |
| Popis: | Endomyocardial fibrosis (EMF) is an endemic disease in tropical areas, characterized by restrictive physiology due to endocardial fibrous thickening of the ventricular chambers. We report the case of a 25-year-old man of African origin who presented with end-stage heart failure due to both diastolic and systolic dysfunction and extensive endocavitary thrombosis as proven by echocardiography and cardiac magnetic resonance. EMF diagnosis was confirmed by endomyocardial biopsy and the patient had eventually cardiac transplantation. The explanted heart revealed, besides features consistent with EMF, transmural post- myocardial infarction scarring, in the absence of significant coronary artery disease, most probably thromboembolic in origin. |
| Databáze: | OpenAIRE |
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