Arteriogenesis in the Pia Matter of the Rat Brain Cortex after Intracerebral Injection of Mesenchymal Stem Cells
| Autor: | A. A. Bilibina, D. P. Dvoretskiy, I. V. Sergeev, I. B. Sokolova |
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| Rok vydání: | 2012 |
| Předmět: |
Male
Pathology medicine.medical_specialty Intracerebral injection Mesenchymal Stem Cell Transplantation General Biochemistry Genetics and Molecular Biology Intracerebral transplantation Microcirculation Cortex (anatomy) medicine Animals Rats Wistar Cerebral Cortex Pia mater business.industry Mesenchymal stem cell Mesenchymal Stem Cells General Medicine Anatomy Rat brain Rats medicine.anatomical_structure Pia Mater Arteriogenesis business |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 154:177-179 |
| ISSN: | 1573-8221 0007-4888 |
| Popis: | We studied the effect of intracerebral transplantation of mesenchymal stem cells on the density of pial arterioles in rat brain cortex. It was shown that intracerebral transplantation although causes damage to about half the area of the ipsilateral pia mater, does not change the density of the microvascular network neither in border region of the injured tissue, nor in the contralateral hemisphere. Intracerebral transplantation of mesenchymal stem cells promoted arteriogenesis in the pia mater of the contralateral hemisphere: density of arterioles in this area was signifi cantly (by about 2.5 times higher) than in other experimental animals. |
| Databáze: | OpenAIRE |
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