Operative outcomes after laparoscopic splenectomy with special reference to prophylactic antibiotics
| Autor: | Masaki Ueno, Tsunemi Matsuda, Hiroshi Kakeya, Hiroji Shinkawa, Shogo Tanaka, Shigekazu Takemura, Shoji Kubo, Katsunari Takifuji, Koichi Yamada, Hiroki Yamaue |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty medicine.drug_class Pleural effusion Antibiotics laparoscopic splenectomy Blood Loss Surgical 030230 surgery Laparoscopic splenectomy 03 medical and health sciences Postoperative Complications 0302 clinical medicine Blood loss medicine Humans Surgical Wound Infection In patient Retrospective Studies Splenic Diseases business.industry Retrospective cohort study General Medicine prophylactic antibiotics Antibiotic Prophylaxis Middle Aged surgical site infection medicine.disease Thrombosis Surgery Treatment Outcome Pancreatic fistula 030220 oncology & carcinogenesis Splenectomy Female Laparoscopy business |
| Zdroj: | Asian Journal of Endoscopic Surgery. 12(4):380-387 |
| ISSN: | 1758-5910 |
| Popis: | Introduction We conducted a retrospective study to investigate the progress of the operative outcome after laparoscopic splenectomy (LS), with a special reference to the administration of prophylactic antibiotics (PA). Methods The study included 123 patients who underwent elective LS. Operative outcomes before and after the operative procedure was standardized and the impact of treatment with PA on surgical-site infection were investigated. Results With regard to complications, wound infection developed in one (0.8%), portal trunk thrombosis in one (0.8%), pancreatic fistula in one (0.8%), postoperative bleeding in two (1.6%), pleural effusion in one (0.8%), and reoperation because of bowel injury in one (0.8%). Although morbidity did not differ between patients in the early (until the end of 2010) and late (after the beginning of 2011) periods, intraoperative blood loss was lower in patients in the late period. During the late period, no patients required conversion to open surgery. The proportion of patients with surgical-site infection did not differ between those who received PA 1 h before the start of surgery and every 3 h during surgery and those who received PA 1 h before the start of surgery, every 3 h during surgery, and twice a day for 24-72 h after surgery. Conclusion Operative outcomes after LS improved after the standardization of the operative procedure. The administration of PA 1 h before surgery and every 3 h during surgery seems to be sufficient to prevent surgical-site infection during LS. |
| Databáze: | OpenAIRE |
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