Neurochemical correlates of synapse density in a Huntington's disease mouse model

Autor: Dahyun Yu, Rocio Gomez-Pastor, Gulin Oz, Katherine Gundry, Jordan Casby, Nicole Zarate, Lynn Eberly
Rok vydání: 2022
Předmět:
Zdroj: Journal of Neurochemistry. 164:226-241
ISSN: 1471-4159
0022-3042
DOI: 10.1111/jnc.15714
Popis: Striatal medium spiny neurons are highly susceptible in Huntington's disease (HD), resulting in progressive synaptic perturbations that lead to neuronal dysfunction and death. Non-invasive imaging techniques, such as proton magnetic resonance spectroscopy (
Databáze: OpenAIRE