Antibacterial activity of optically transparent nanocomposite films based on chitosan or its derivatives and silver nanoparticles
| Autor: | Susana C. M. Fernandes, Ricardo J.B. Pinto, Carmen S. R. Freire, Carlos Pascoal Neto, Patrizia Sadocco, Jessica Causio, Tito Trindade |
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| Přispěvatelé: | Universidade de Aveiro |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Staphylococcus aureus
Silver Nanoparticle Metal Nanoparticles 02 engineering and technology Microbial Sensitivity Tests macromolecular substances 010402 general chemistry Borohydride 01 natural sciences Biochemistry Silver nanoparticle Analytical Chemistry Nanocomposites Chitosan chemistry.chemical_compound Microscopy Electron Transmission Escherichia coli Thin film Particle Size Nanocomposite Chemistry Organic Chemistry technology industry and agriculture General Medicine 021001 nanoscience & nanotechnology 0104 chemical sciences Anti-Bacterial Agents carbohydrates (lipids) Klebsiella pneumoniae Nanomedicine [CHIM.POLY]Chemical Sciences/Polymers Microscopy Electron Scanning Particle size 0210 nano-technology Antibacterial activity Nuclear chemistry |
| Zdroj: | Carbohydrate Research Carbohydrate Research, Elsevier, 2012, 348, pp.77-83. ⟨10.1016/j.carres.2011.11.009⟩ |
| ISSN: | 0008-6215 |
| DOI: | 10.1016/j.carres.2011.11.009⟩ |
| Popis: | cited By 72; International audience; Colloidal silver nanoparticles (NPs) were prepared using the citrate and borohydride reduction methods and were then investigated as fillers in three matrices: unmodified chitosan, water-soluble chitosan and a N-alkyl chitosan derivative. The nanocomposites were used to prepare cast thin films (9-19 μm thickness) and characterized for their optical and antimicrobial properties. The optical properties of the materials were adjusted either by varying the Ag NPs content in the films (0.5-3.9% w/w) or by using samples of Ag NPs with distinct particle size distributions. The antibacterial activity towards both Gram-positive (Staphylococcus aureus) and Gram-negative bacteria (Klebsiella pneumoniae and Escherichia coli) was investigated for the various composites. For the unmodified chitosan nanocomposites, the bactericidal effect depended on their Ag content while such an effect was always observed for water-soluble chitosan and N-alkyl chitosan based materials. This research provides a basis for the evaluation of chitosan/silver composites in applications requiring flexible films with tuned optical properties and antimicrobial activity. © 2011 Elsevier Ltd. All rights reserved. |
| Databáze: | OpenAIRE |
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