Fabrication of Microchannel Structures in Fluorinated Ethylene Propylene
| Autor: | Stephen G. Weber, Eskil Sahlin, Amy T. Beisler, Steven J. Woltman |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Microchannel
Fabrication Polytetrafluoroethylene Microchemistry Biuret Reaction Analytical chemistry Equipment Design Article Analytical Chemistry chemistry.chemical_compound Fluorinated ethylene propylene chemistry Chemical engineering Fluoropolymer Tetrafluoroethylene Microreactor Peptides Layer (electronics) Enkephalin Leucine |
| Zdroj: | Analytical Chemistry. 74:4566-4569 |
| ISSN: | 1520-6882 0003-2700 |
| DOI: | 10.1021/ac025622c |
| Popis: | A new technique for fabrication of channel structures with diameters down to 13 microm in fluorinated ethylene propylene (also known as poly(tetrafluoroethylene-co-hexafluoropropylene), FEP) is described. The technique is based on the unique property of a dual-layer fluoropolymer tubing consisting of an outer layer of poly(tetrafluoroethylene) (PTFE) and an inner layer of FEP. When heated (350 degrees C), the outer PTFE layer shrinks while the inner FEP layer melts, resulting in filling of all empty space inside the tubing with FEP. The channel structures are formed using tungsten wires as templates that are pulled out after completion of the shrinking and melting process. While several analytical devices have been reproducibly prepared and shown to function, this report describes a single example. A microreactor coupled to an electrochemical flow cell detects the biuret complex of the natively electroinactive peptide des-Tyr-Leu-enkephalin. |
| Databáze: | OpenAIRE |
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