Identification of Polymorphisms in the Osteopontin Gene and Their Associations with Certain Semen Production Traits of Water Buffaloes in the Brazilian Amazon
| Autor: | K. B. Nunes, G. M. F. de Camargo, W. G. Vale, Humberto Tonhati, S. T. Rolim Filho, E M Barbosa, K. C. de Sousa, Rusbel Raúl Aspilcueta-Borquis, Diercles Francisco Cardoso, Haroldo Francisco Lobato Ribeiro |
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| Rok vydání: | 2013 |
| Předmět: |
Male
endocrine system Buffaloes Genotype media_common.quotation_subject Single-nucleotide polymorphism Fertility Semen Biology Polymorphism Single Nucleotide Linkage Disequilibrium Andrology Endocrinology Animals SNP Allele Alleles Sperm motility media_common Genetics urogenital system Sperm Gene Expression Regulation Osteopontin Animal Science and Zoology Brazil Biotechnology |
| Zdroj: | Reproduction in Domestic Animals. 48:705-709 |
| ISSN: | 0936-6768 |
| DOI: | 10.1111/rda.12144 |
| Popis: | Contents The osteopontin gene may influence the fertility of water buffaloes because it is a protein present in sperm. The aim of this work was to identify polymorphisms in this gene and associate them with fertility parameters of animals kept under extensive grazing. A total of 306 male buffaloes older than 18 months, from two farms, one in the state of Amapa and the other in the state of Para, Brazil were used in the study. Seven SNPs were identified in the regions studied. The polymorphisms were in gene positions 1478, 1513 and 1611 in the region 5′upstrem and positions 6690, 6737, 6925 and 6952 in the region amplified in intron 5. The SNPs were associated with the traits, namely scrotal circumference, scrotal volume, sperm motility, sperm concentration and sperm pathology. There were significant SNPs (p |
| Databáze: | OpenAIRE |
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