Catatonia Associated With Lorazepam Withdrawal

Autor: Joseph Bishop, Rodrigo Escalona, Susan G. Glover, Aida Saldivia
Rok vydání: 1997
Předmět:
Zdroj: Psychosomatics. 38:148-150
ISSN: 0033-3182
DOI: 10.1016/s0033-3182(97)71484-1
Popis: Catatonia is a heterogeneous syndrome that varies in etiology, presentation, course, and sequelae. Some have suggested conceptualizing catatonia as malignant when associated with autonomic instability or hyperthermia and simple in the absence of these signs.· Whereas malignant catatonia is a potentially lethal medical emergency, simple catatonia may be quite subtle and go unrecognized. Regardless of type, catatonia has been associated with many different psychiatric and medical conditions. Historically, it has been linked with psychotic illness but likely occurs more frequently in the course of affective disorders. Although catatonia due to medical conditions is rarely precipitated by a single factor, the potential etiologies may be subdivided into the categories of neurologic, metabolic, and substance-induced. In the latter, reactions to drugs such as antipsychotics, disulfuram, corticosteroids, alcohol, and phencyclidine have been reportedY Benzodiazepines (BZDs), particularly lorazepam, have been used in inpatient psychiatric settings to treat catatonic symptoms. However, there is to the best of our knowledge only one case report ofcatatonic symptoms occurring during the course of BZD withdrawalS and none specifically during lorazepam withdrawal. We discuss the development of simple catatonia and its treatment response in the case ofa patient with schizophrenia when lorazepam was tapered and discontinued. Both diagnosis and treatment re
Databáze: OpenAIRE