Dyslipidemia in Special Ethnic Populations
| Autor: | Jia Pu, Robert J. Romanelli, Latha Palaniappan, Vani Nimbal, Kristen M.J. Azar, Beinan Zhao, Stephen P. Fortmann, Katherine G. Hastings |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Gerontology
Endocrinology Diabetes and Metabolism Ethnic group Ethnic populations 030204 cardiovascular system & hematology Stroke mortality Global Health Article 03 medical and health sciences Chd mortality 0302 clinical medicine Endocrinology Lifestyle modification Risk Factors Ethnicity Prevalence medicine Global health Humans 030212 general & internal medicine Disease management (health) Dyslipidemias business.industry Disease Management nutritional and metabolic diseases General Medicine medicine.disease Lipids Coronary heart disease Racial/ethnic difference Hydroxymethylglutaryl-CoA Reductase Inhibitors Cardiology and Cardiovascular Medicine business Dyslipidemia Demography |
| Zdroj: | Endocrinol Metab Clin North Am |
| ISSN: | 1558-4410 |
| Popis: | This manuscript reviewed racial/ethnic differences in dyslipidemia, including prevalence of dyslipidemia, its relation to CHD and stroke mortality rates, response to lipid-lowering agents, and lifestyle modification. In particular, among all racial/ethnic groups, Asian Indians, Filipinos and Hispanics are at higher risk for dyslipidemia, which is consistent with the higher coronary heart disease (CHD) mortality rates in these groups. In addition, compared to other racial/ethnic groups, statins may have a higher efficacy for Asians. Studies suggest lower starting dosage in Asians, but the data are mixed. Genetic differences in statin metabolism can in part explain this racial/ethnic difference in statin sensitivity and adverse effects. Furthermore, lifestyle modification is recommended as part of dyslipidemia control and management. Both African Americans and Hispanics have more sedentary behavior and less favorable diet profile. Hispanic subgroups (i.e. Mexican, Puerto Rican, etc.) and Asian (i.e. Chinese, South Asian, etc.) subgroups should be disaggregated for lifestyle interventions due to cultural differences among the subgroups. Further studies are needed to better understand racial/ethnic-specific risk factors contributing to the observed differences in dyslipidemia, CHD, and stroke. Culturally-tailored prevention and intervention should be provided to the minority populations with elevated risk for dyslipidemia and considerably more research is needed to determine the best approaches to helping specific subgroups. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|