The Association of Obesity, Type 2 Diabetes, and Hypertension with Severe Coronavirus Disease 2019 on Admission Among Mexican Patients

Autor: Rosaura Gutiérrez-Vargas, Dwigth D. Dyer-Leal, Christian A. Zaragoza-Jimenez, Tonatiuh Barrientos-Gutiérrez, Simón Barquera, Ruy Lopez-Ridaura, José Luis Alomía-Zegarra, Hugo López-Gatell, Edgar Denova-Gutiérrez, Ricardo Cortes-Alcala, Juan A Rivera, Kathia Rodríguez-González, Tania Villa-Reyes, Carlos Escondrillas-Maya
Rok vydání: 2020
Předmět:
Adult
Male
medicine.medical_specialty
Endocrinology
Diabetes and Metabolism
Pneumonia
Viral
Medicine (miscellaneous)
030209 endocrinology & metabolism
Type 2 diabetes
Severity of Illness Index
Betacoronavirus
03 medical and health sciences
0302 clinical medicine
Endocrinology
Risk Factors
COVID‐19
Diabetes mellitus
Intensive care
Internal medicine
Epidemiology
Severity of illness
medicine
Humans
Obesity
030212 general & internal medicine
Mexico
Pandemics
Aged
Retrospective Studies
Nutrition and Dietetics
SARS-CoV-2
business.industry
Respiratory disease
Age Factors
COVID-19
Retrospective cohort study
Original Articles
Middle Aged
medicine.disease
Type 2 Diabetes
Hospitalization
Logistic Models
Diabetes Mellitus
Type 2
Hypertension
Mexican population
Female
Original Article
Coronavirus Infections
business
Zdroj: Obesity (Silver Spring, Md.)
Obesity
ISSN: 1930-739X
1930-7381
DOI: 10.1002/oby.22946
Popis: OBJECTIVE: This study's aim was to explore the association of obesity, type 2 diabetes, and hypertension with severe coronavirus disease 2019 (COVID-19) on admission. METHODS: In the present study, a total of 23,593 patient samples were evaluated by a laboratory from the Mexican Institute of Epidemiological Diagnosis and Reference. Of these, 18,443 were negative for COVID-19, 3,844 were positive for COVID-19, and 1,306 were positive for other respiratory viruses. Severe types of respiratory disease were defined by the presence of pneumonia and other organ failure that requires intensive care. Multivariable logistic regression models were used to explore factors associated with severe COVID-19 on admission. RESULTS: Patients who tested positive for COVID-19 had a higher proportion of obesity (17.4%), diabetes (14.5%), and hypertension (18.9%) compared with those without a confirmed diagnosis. Compared with patients without obesity, those with obesity showed a 1.43-fold higher odds of developing severe COVID-19 on admission, whereas subjects with diabetes and hypertension showed a 1.87-fold and 1.77-fold higher odds of developing severe COVID-19 on admission, respectively. CONCLUSIONS: Obesity, diabetes, and hypertension were significantly associated with severe COVID-19 on admission and the association of obesity was stronger in patients < 50 years of age.
Databáze: OpenAIRE
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