Heart rate, arterial pressure and propofol-sparing effects of guaifenesin in dogs

Autor: Teodora S. Hristova, Stephanie CJ. Keating, Annette M. McCoy, Danielle E. Strahl-Heldreth, Graeme M. Doodnaught, Kelly M. Sieja, Kelly S. Swanson
Rok vydání: 2022
Předmět:
Zdroj: Veterinary anaesthesia and analgesia.
ISSN: 1467-2995
Popis: To evaluate the heart rate (HR) and systemic arterial pressure (sAP) effects, and propofol induction dose requirements in healthy dogs administered propofol with or without guaifenesin for the induction of anesthesia.Prospective blinded crossover experimental study.A total of 10 healthy adult female Beagle dogs.Dogs were premedicated with intravenous (IV) butorphanol (0.4 mg kgPropofol doses (mean ± standard deviation) for treatments saline, G50 and G100 were 3.3 ± 1.0, 2.7 ± 0.7 and 2.1 ± 0.8 mg kgWhen administered as a co-induction agent in dogs, guaifenesin reduced propofol requirements for tracheal intubation. HR increased and sAP and f
Databáze: OpenAIRE