Fondaparinux vs. enoxaparin for the prevention of venous thromboembolism after total hip replacement: A meta-analysis
| Autor: | Yan Qian, Zhou Ling, Hui‑Juan Qian, San‑Lian Hu, Wen‑Jun Dong |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Cancer Research
medicine.medical_specialty Deep vein venous thromboembolism 030204 cardiovascular system & hematology Cochrane Library Fondaparinux 03 medical and health sciences 0302 clinical medicine Immunology and Microbiology (miscellaneous) Internal medicine medicine cardiovascular diseases 030212 general & internal medicine business.industry fondaparinux enoxaparin Articles General Medicine medicine.disease Thrombosis Confidence interval total hip replacement Surgery medicine.anatomical_structure Meta-analysis Relative risk business Venous thromboembolism medicine.drug |
| Zdroj: | Experimental and Therapeutic Medicine |
| ISSN: | 1792-1015 1792-0981 |
| DOI: | 10.3892/etm.2016.3351 |
| Popis: | The aim of the study was to compare the efficacy and safety profiles of fondaparinux and enoxaparin in preventing the venous thromboembolism (VTE) after total hip replacement. A systematic literature search in the PubMed, EMBASE and Cochrane library databases was performed to identify relevant articles published in English since inception up to November 16, 2014. The efficacy outcomes were all VTE, total deep vein thrombosis (DVT) and symptomatic VTE, while the safety outcome was major bleeding. Four eligible studies were included in the meta-analysis. The incidences of total VTEs and DVTs were significantly decreased with the use of fondaparinux when compared to enoxaparin [total VTE: risk ratio (RR)=0.59, 95% confidence interval (CI): 0.46–0.74, P |
| Databáze: | OpenAIRE |
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