Biodegradation of 4-(1-nonyl)phenol by axenic cultures of the yeast Candida aquaetextoris: Identification of microbial breakdown products and proposal of a possible metabolic pathway
| Autor: | Giorgio Catelani, Felicia D'Andrea, Stefania Frassinetti, Monica Agnolucci, Giovanni Vallini |
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| Jazyk: | angličtina |
| Rok vydání: | 2001 |
| Předmět: |
Biology
Microbiology Biomaterials BIOREMEDIATION ALKYLPHENOLS chemistry.chemical_compound Candida aquaetextoris Organic chemistry Phenol Alkylphenols Candida aquaetextoris Microbial bioremediation 4-(1-nonyl)phenol Trans-4-hydroxycinnamic acid Yeast-induced biodegradation Microbial biodegradation Axenic Waste Management and Disposal 4-(1-NONYL)PHENOL BIODEGRADATION Microbial bioremediation Substrate (chemistry) Biodegradation biology.organism_classification 4-(1-nonyl)phenol Yeast YEAST-INDUCED DEGRADATION Metabolic pathway TRANS-4-HYDROXYCINNAMIC ACID Biochemistry chemistry Yeast-induced biodegradation Energy source |
| Popis: | Candida aquaetextoris, a yeast recently described for its ability to use 4-(1-nonyl)phenol (pNP) as the sole carbon and energy source in aerobic conditions, has been studied in order to determine the degradation products deriving from the growth on such a compound which is of environmental concern because of its proved toxicity to several organisms. Two main metabolites, namely trans-4-hydroxy-cinnamic acid and 4-hydroxy-acetophenone (4-acetylphenol), have been identified through either TLC and NMR spectrometry analyses of liquid substrate from cultures of C. aquaetextoris grown on pNP, with 4-acetylphenol that accumulates without any further degradation. These findings suggest that C. aquaetextoris might metabolise pNP via terminal oxidation of the alkyl chain, followed by a β-oxidation pathway. On the basis of this evidence, a novel metabolic route for the microbial degradation of 4-(1-nonyl)phenol, at least in certain yeasts, is proposed. |
| Databáze: | OpenAIRE |
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