The impact of combined nutraceutical supplementation on quality of life and metabolic changes during the menopausal transition: a pilot randomized trial
| Autor: | Inbal Dona Amar, Carolina Bottoni, Giovanni Scambia, Paola Villa, Giorgia Dinoi, Maria Cristina Moruzzi, Clelia Cipolla, Antonio Lanzone |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Hot flushes Menopause Nutraceuticals Phytoestrogens Soy isoflavones Obstetrics and Gynecology Rome Pilot Projects 030204 cardiovascular system & hematology Irritability law.invention 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Nutraceutical Obstetrics and gynaecology Quality of life Randomized controlled trial law Internal medicine medicine Humans Gynecology Plants Medicinal 030219 obstetrics & reproductive medicine business.industry General Medicine Middle Aged medicine.disease Micronutrient Isoflavones Treatment Outcome Settore MED/40 - GINECOLOGIA E OSTETRICIA Italy chemistry Dietary Supplements Hot Flashes Quality of Life Female medicine.symptom business Phytotherapy |
| Zdroj: | Archives of Gynecology and Obstetrics. 296:791-801 |
| ISSN: | 1432-0711 0932-0067 |
| DOI: | 10.1007/s00404-017-4491-9 |
| Popis: | The aim of this study was to assess the efficacy of a combined nutraceutical supplement on symptoms and early metabolic alterations during the menopausal transition. This pilot randomized study was conducted at the service for menopause disorders of the Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy. Ninety women in menopausal transition who attended our service with menopausal symptoms were enrolled in the study. Sixty patients, randomly assigned to the treatment group, were prescribed one daily tablet of a combined nutraceutical compound with phytoestrogen substances, vitamins, micronutrients and passion flower herbal medicine for 6 months. Thirty patients did not receive any treatment and comprised the control group. The intensity of perimenopausal symptoms was assessed by the modified Kuppermann Index (KI) at enrollment and at 3 and 6 months of treatment. At baseline and at the end of the study, patients underwent a clinical evaluation, a pelvic ultrasound and analysis of blood samples. In the nutraceutical supplemented group, a significant reduction in menopausal symptoms was demonstrated according to the KI after 3 and 6 months of supplementation (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink