Synthesis of racemic 6,10,14-trimethylpentadecan-2-ol, a pheromone of rice moth and 5,9,13-trimethyltetradecanoic acid, a component of marine sponge from a common intermediate
| Autor: | Sneha S. Rane, V.R. Mamdapur, M.S. Chadha |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Magnetic Resonance Spectroscopy
Stereochemistry Clinical Biochemistry Pharmaceutical Science Moths Biochemistry Cinachyrella alloclada Pheromones chemistry.chemical_compound Drug Discovery Animals Molecular Biology Allylmagnesium bromide biology Corcyra cephalonica Molecular Structure Component (thermodynamics) Terpenes Organic Chemistry Fatty Acids Stereoisomerism biology.organism_classification Porifera Sponge chemistry Rice moth Alcohols Molecular Medicine Pheromone Knoevenagel condensation |
| Zdroj: | Bioorganicmedicinal chemistry. 1(6) |
| ISSN: | 0968-0896 |
| Popis: | A facile synthesis of dl -6,10,14-trimethylpentadecan-2-ol ( 1 ) a pheromone component of rice moth, Corcyra cephalonica Stainton and 5,9,13-trimethyltetradecanoic acid ( 2 ) a component of marine sponge, Cinachyrella alloclada Uliczka, using a common intermediate, hexahydrofarnesol is accomplished. The salient features for 1 are: Grignard coupling of 5 with allylmagnesium bromide and oxymercuration-demercuration whereas for 2 they are: Knoevenagel condensation and subsequent hydrogenation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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