Changes in pupil diameter are correlated with the occurrence of pareidolias in patients with dementia with Lewy bodies
Autor: | Ryusuke Inoue, Makoto Uchiyama, Yumi Suzuki, Etsuro Mori, Kazumi Hirayama, Mika Otsuki, Osamu Iizuka, Tatsuo Shimomura, Shinya Sakai, Yoshiyuki Nishio, Hiromi Fujii |
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Rok vydání: | 2017 |
Předmět: |
Lewy Body Disease
Male medicine.medical_specialty Hallucinations fast fourier transform Fixation Ocular Audiology 050105 experimental psychology Pupil 03 medical and health sciences 0302 clinical medicine Pareidolia medicine Saccades Humans 0501 psychology and cognitive sciences In patient pareidolias Aged Aged 80 and over Dementia with Lewy bodies Optical illusion General Neuroscience 05 social sciences Clinical Neuroscience hallucination medicine.disease Illusions pupil diameter Visual Hallucination Fixation (visual) Female sense organs Psychology dementia with Lewy bodies 030217 neurology & neurosurgery Utterance Photic Stimulation |
Zdroj: | Neuroreport |
ISSN: | 1473-558X |
Popis: | Pareidolias are visual illusions of meaningful objects, such as faces and animals, that arise from ambiguous forms embedded in visual scenes. Pareidolias and visual hallucinations have been suggested to have a common underlying neural mechanism in patients with dementia with Lewy bodies (DLB). The aim of the present study was to find an externally observable physiological indicator of pareidolias. Using a pareidolia test developed by Uchiyama and colleagues, we evoked pareidolias in patients with DLB and recorded the resultant changes in the diameters of their pupil. The time frequencies of changes in pupil diameters preceding pareidolic utterances and correct utterances by the patients, as well as correct utterances by healthy control participants, were analyzed by a fast Fourier transform program. The power at time frequencies of 0-0.46 Hz was found to be greatest preceding pareidolic utterances in patients with DLB, followed by that preceding correct utterances in control participants, followed by that preceding correct utterances in patients with DLB. When the changes in power preceding the utterance were greater than the median value of correct utterances by the control group, the frequency of pareidolic utterances was significantly greater than that of correct utterances and when the changes were the same as or lower than the median value, the frequency of correct utterances was significantly greater than that of pareidolic utterances. Greater changes in power preceding the utterance at time frequencies of 0-0.46 Hz may thus be an externally observable physiological indicator of the occurrence of pareidolias. |
Databáze: | OpenAIRE |
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