A randomized controlled trial of emotion regulation therapy for psychologically distressed caregivers of cancer patients
Autor: | Mia Skytte O'Toole, Robert Zachariae, Douglas S. Mennin, Hanne Krogh Rose, Britta Weber, David M. Fresco, Allison J. Applebaum |
---|---|
Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
050103 clinical psychology
Cancer Research medicine.medical_specialty media_common.quotation_subject Population Article law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial Quality of life law Internal medicine medicine 0501 psychology and cognitive sciences education media_common education.field_of_study business.industry 05 social sciences Cognition Caregiver burden Confidence interval Oncology 030220 oncology & carcinogenesis Rumination medicine.symptom Worry business |
Zdroj: | O'Toole, M S, Mennin, D S, Applebaum, A, Weber, B, Rose, H, Fresco, D M & Zachariae, R 2020, ' A randomized controlled trial of emotion regulation therapy for psychologically distressed caregivers of cancer patients ', JNCI Cancer Spectrum, vol. 4, no. 1, pkz074 . https://doi.org/10.1093/jncics/pkz074 JNCI Cancer Spectrum |
Popis: | Background Previous cognitive behavioral therapies for informal caregivers (ICs) have produced negligible effects. The purpose of this study was to evaluate, in a randomized controlled trial, the efficacy of Emotion Regulation Therapy adapted for caregivers (ERT-C) on psychological and inflammatory outcomes in psychologically distressed ICs and the cancer patients cared for. Methods A total of 81 ICs with elevated psychological distress were randomly assigned to ERT-C or a waitlist condition and assessed pre-, mid-, and post-treatment. In 52 cases, the patient cared for by the IC was included. Patients did not receive ERT-C. Both the ERT-C and waitlist groups were followed 3 and 6 months post-treatment. Data were analyzed with multilevel models, and P values were two-sided. Results Compared with ICs in the waitlist condition, ICs in the ERT-C condition experienced medium to large statistically significant reductions in psychological distress (Hedge’s g = 0.86, 95% confidence interval [CI] = 0.40 to 1.32, P < .001), worry (g = 0.96, 95% CI = 0.50 to 1.42, P < .001), and caregiver burden (g = 0.53, 95% CI = 0.10 to 1.99, P = .007) post-treatment. No statistically significant effects were found for rumination (g = 0.24, 95% CI = −0.20 to 0.68, P = .220). Results concerning caregiver burden were maintained through 6 months follow-up. Although the effects on psychological distress and worry diminished, their end-point effects remained medium to large. No statistically significant effects on systemic inflammation were detected (C-reactive protein: g = .17, 95% CI = −0.27 to 0.61, P = .570; interleukin-6: g = .35, 95% CI = −0.09 to 0.79, P = .205; tumor necrosis factor-alpha: g = .11, 95% CI = −0.33 to 0.55, P = .686). Patients whose ICs attended ERT-C experienced a large increase in quality of life post-treatment (g = 0.88, 95% CI = 0.18 to 1.58, P = .017). Conclusions To our knowledge, this is the first randomized controlled trial evaluating the efficacy of ERT-C for ICs. Given the previous disappointing effects of other cognitive behavioral therapies for this population, the present findings are very encouraging. Identifying ICs with elevated psychological distress and providing them with relevant psychotherapy appears an important element of comprehensive cancer care. |
Databáze: | OpenAIRE |
Externí odkaz: |