The Effect of Mushroom Beta-Glucans from Solid Culture of Ganoderma lucidum on Inhibition of the Primary Tumor Metastasis
| Autor: | Cheng Jeng Tai, Shiu-Nan Chen, Ching-Sheng Chang, Sherwin Chen, Chung Lun Lu, William Wang, Ming Hsin Hung |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Mushroom
Pathology medicine.medical_specialty Article Subject business.industry medicine.medical_treatment Lewis lung carcinoma lcsh:Other systems of medicine lcsh:RZ201-999 medicine.disease Primary tumor Metastasis Radiation therapy Hair loss Complementary and alternative medicine Oral administration medicine Cancer research Cytotoxicity business Research Article |
| Zdroj: | Evidence-based Complementary and Alternative Medicine : eCAM Evidence-Based Complementary and Alternative Medicine, Vol 2014 (2014) |
| ISSN: | 1741-427X |
| DOI: | 10.1155/2014/252171 |
| Popis: | This study evaluates the effect of mushroom beta-glucans (MBGS) derived from solid culture ofGanoderma lucidumon tumor inhibition by examining size of the primary tumor and rate of metastasis in Lewis lung carcinoma (LLC) bearing mice (C57BL/6), given oral administration of MBGS with radiation therapy. A previous result showed that MBGS enhances NK cell-mediated cytotoxicity in mice without LLC bearing in advance. Furthermore, applications of MBGS in conjunction with radiation therapy were effective in controlling tumor growth, and rate of metastasis, life threatening, and can potentially serve as a protective factor for wounds and hair loss that resulted from the overgrowth of primary tumor in LLC bearing mice. |
| Databáze: | OpenAIRE |
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