Erythema elevatum diutinum with rare distribution as a first clinical sign of non-Hodgkin's lymphoma: a novel association?
| Autor: | Thrasivoulos George Tzellos, Apostolos I. Hatzitolios, Martha Apostolopoulou, Evaggelos Psomas, Vasileios Tzalokostas, Christos Savopoulos, Athanasios Papadopoulos, Georgia Kaiafa |
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| Rok vydání: | 2008 |
| Předmět: |
Male
medicine.medical_specialty Pathology Erythema Paraproteinemias Dermatology Diagnosis Differential immune system diseases Prednisone hemic and lymphatic diseases Antineoplastic Combined Chemotherapy Protocols medicine Humans skin and connective tissue diseases Cyclophosphamide Aged integumentary system business.industry Lymphoma Non-Hodgkin General Medicine medicine.disease Lymphoma Non-Hodgkin's lymphoma IgM Monoclonal Gammopathy Erythema elevatum diutinum Doxorubicin Vincristine Differential diagnosis medicine.symptom business Vasculitis medicine.drug |
| Zdroj: | The Journal of dermatology. 35(5) |
| ISSN: | 0385-2407 |
| Popis: | We present a case of a 78-year-old man with erythema elevatum diutinum as a first clinical sign of non-Hodgkin's lymphoma. The patient developed erythema elevatum diutinum with an unusual distribution involving the trunk. Erythema elevatum diutinum is a rare dermatosis that is considered to be a localized, low-grade form of leukocytoclastic vasculitis associated with neoplastic, autoimmune and infectious processes. It is probably mediated by immune complexes. Recent studies report hematological disease as the most common factor associated with erythema elevatum diutinum. Many hematological diseases, such as myeloma, myelodysplastic syndrome and immunoglobulin (Ig)A monoclonal gammopathy, have been reported in association with erythema elevatum diutinum, but none with IgM monoclonal gammopathy and only one with malignant lymphoma. We would like to add IgM monoclonal gammopathy and non-Hodgkin's lymphoma as one of the diseases associated with erythema elevatum diutinum considering that the activity of erythema elevatum diutinum and non-Hodgkin's lymphoma fluctuated in parallel in the present case. |
| Databáze: | OpenAIRE |
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