Type 2 diabetes after a pregnancy with gestational diabetes among first nations women in Australia: The PANDORA study
| Autor: | Federica Barzi, Joanna Kelaart, Elizabeth Moore, Anna Wood, Elizabeth L M Barr, Sian Graham, Zhong X. Lu, Jeremy Oats, Alex Brown, Marie Kirkwood, Harold David McIntyre, Elizabeth Death, Matthew J.L. Hare, Christine Connors, Louise J. Maple-Brown, Jacqueline Boyle, Danielle K. Longmore, Paul Zimmet, Jonathan E. Shaw, Kerin O'Dea, Angela Titmuss |
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| Přispěvatelé: | Wood, Anna J, Boyle, Jacqueline A, Barr, Elizabeth LM, Barzi, Federica, O'Dea, Kerin, Maple-Brown, Louise J |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Endocrinology Diabetes and Metabolism Pregnancy in Diabetics Type 2 diabetes Prediabetic State Endocrinology Pregnancy Risk Factors Diabetes mellitus Internal Medicine medicine Humans Cumulative incidence Prospective Studies Prediabetes Aged Indigenous health Obstetrics business.industry Incidence (epidemiology) Postpartum Period General Medicine medicine.disease Gestational diabetes Diabetes Gestational Diabetes Mellitus Type 2 Female gestational diabetes business Body mass index diabetes in pregnancy |
| Zdroj: | Diabetes Research and Clinical Practice. 181:109092 |
| ISSN: | 0168-8227 |
| DOI: | 10.1016/j.diabres.2021.109092 |
| Popis: | Aims: To determine among First Nations and Europid pregnant women the cumulative incidence and predictors of postpartum type 2 diabetes and prediabetes and describe postpartum cardiovascular disease (CVD) risk profiles. Methods: PANDORA is a prospective longitudinal cohort of women recruited in pregnancy. Ethnic-specific rates of postpartum type 2 diabetes and prediabetes were reported for women with diabetes in pregnancy (DIP), gestational diabetes (GDM) or normoglycaemia in pregnancy over a short follow-up of 2.5 years (n = 325). Pregnancy characteristics and CVD risk profiles according to glycaemic status, and factors associated with postpartum diabetes/prediabetes were examined in First Nations women. Results: The cumulative incidence of postpartum type 2 diabetes among women with DIP or GDM were higher for First Nations women (48%, 13/27, women with DIP, 13%, 11/82, GDM), compared to Europid women (nil DIP or GDM p < 0.001). Characteristics associated with type 2 diabetes/prediabetes among First Nations women with GDM/DIP included, older age, multiparity, family history of diabetes, higher glucose values, insulin use and body mass index (BMI). Conclusions: First Nations women experience a high incidence of postpartum type 2 diabetes after GDM/DIP, highlighting the need for culturally responsive policies at an individual and systems level, to prevent diabetes and its complications. Refereed/Peer-reviewed |
| Databáze: | OpenAIRE |
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