EV71 vaccination impact on the incidence of encephalitis in patients with hand, foot and mouth disease
| Autor: | Ji-an Li, Xiuzhen Nie, Liyan Liu, Xiuzhi Yin, Daoyan Xu, Shihua Liu, Na Li, Ping Wang, Shuangshuang Song, Ai-Wei Lin, Shaoning Wang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Pediatrics
medicine.medical_specialty China 030231 tropical medicine Immunology Short Report Hand-foot-and-mouth disease 03 medical and health sciences 0302 clinical medicine stomatognathic system Immunology and Allergy Medicine Humans In patient 030212 general & internal medicine Pharmacology Foot-and-mouth disease business.industry Incidence (epidemiology) Incidence Vaccination Infant medicine.disease Enterovirus A Human Encephalitis business Hand Foot and Mouth Disease |
| Zdroj: | Hum Vaccin Immunother |
| Popis: | In order to analyze the effect of EV71 vaccination on the incidence of encephalitis in patients with HFMD, 292 cases were vaccinated, and 2,486 cases were not vaccinated which were collected in 2018 and 2019. It shows that the incidence rate of encephalitis in vaccinated patients was significantly lower than that in non-vaccinated (P = .028), which suggests that EV71 vaccine has a protective effect on the occurrence of encephalitis. But some EV71 vaccinated patients still developed into encephalitis showed that they had not produced protection or protection was weak against EV71-related encephalitis; the reasons require further investigation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|