Corytophanids Replaced the Pleurodont XY System with a New Pair of XY Chromosomes
Autor: | Fausto R. Méndez-de-la-Cruz, Andrés Lira-Noriega, Armando Acosta, Oswaldo Hernández-Gallegos, Luis A. Rodriguez-Miranda, Diana Aguilar-Gómez, Mariana Gutiérrez-Mariscal, Gabriel Suárez-Varón, Diego Cortez |
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Rok vydání: | 2019 |
Předmět: |
Male
0106 biological sciences Basiliscus vittatus XY chromosomes Y chromosome 010603 evolutionary biology 01 natural sciences Anolis 03 medical and health sciences biology.animal Genetics Animals sex chromosome evolution Phylogeny Ecology Evolution Behavior and Systematics X chromosome 030304 developmental biology sex chromosome system turnovers 0303 health sciences Sex Chromosomes Dosage compensation biology Lizard Gene Expression Profiling Chromosome Lizards Sex Determination Processes biology.organism_classification Chromosome 17 (human) Evolutionary biology casque-headed lizards Female Transcriptome Research Article |
Zdroj: | Genome Biology and Evolution |
ISSN: | 1759-6653 |
Popis: | Almost all lizard families in the pleurodont clade share the same XY system. This system was meticulously studied in Anolis carolinensis, where it shows a highly degenerated Y chromosome and a male-specific X chromosome dosage compensation mechanism. Corytophanids (casque-headed lizards) have been proposed as the only family in the pleurodont clade to lack the XY system. In this study, we worked with extensive genomic and transcriptomic data from Basiliscus vittatus, a member of the Corytophanidae family that inhabits the tropical rainforests of Mexico. We confirmed that B. vittatus underwent a sex chromosome system turnover, which consisted in the loss of the pleurodont XY system and the gain of a new pair of XY chromosomes that are orthologous to chicken chromosome 17. We estimated the origin of the sex chromosome system to have occurred ∼63 Ma in the ancestor of corytophanids. Moreover, we identified 12 XY gametologues with particular attributes, such as functions related to the membrane and intracellular trafficking, very low expression levels, blood specificity, and incomplete dosage compensation in males. |
Databáze: | OpenAIRE |
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