Urodynamic findings in patients with Creutzfeldt–Jakob disease: a case report
| Autor: | Syuichi Kamijima, Masashi Yano, Hiroyoshi Suzuki, Megumi Sugiyama, Haruka Nakamura, Naoto Kamiya, Lee Fang-ching, Ryuji Sakakibara, Fuyuki Tateno, Osamu Takahashi |
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| Rok vydání: | 2016 |
| Předmět: |
Male
0301 basic medicine Nephrology medicine.medical_specialty Pediatrics animal diseases Urology Urinary system medicine.medical_treatment Urinary incontinence Disease Creutzfeldt-Jakob Syndrome Urinary catheterization 03 medical and health sciences 0302 clinical medicine Internal medicine mental disorders medicine Humans Urinary Bladder Neurogenic Aged Intelligence Tests Neurologic Examination Urinary Bladder Overactive Urinary retention business.industry Functional incontinence Diagnostic Techniques Urological Urinary Retention nervous system diseases Urodynamics Urinary Incontinence 030104 developmental biology Female Symptom Assessment medicine.symptom Urinary Catheterization business 030217 neurology & neurosurgery |
| Zdroj: | International Urology and Nephrology. 48:1579-1583 |
| ISSN: | 1573-2584 0301-1623 |
| DOI: | 10.1007/s11255-016-1344-6 |
| Popis: | Urinary dysfunction in Creutzfeldt-Jakob disease (CJD) patients is attributed to functional incontinence, since they often have immobility and loss of motivation. In contrast, previously no urodynamic findings are available in CJD patients.We had 2 CJD patients who had urinary frequency and urinary retention. We performed urodynamics with the spouse's informed consent in order to explore the mechanism of urinary dysfunction in those cases. Case 1 had typical acute cognitive deterioration with incontinence and urinary retention, while case 2 had subacute cognitive deterioration (that started after admission) and nocturia. The urodynamic findings were diverse. One feature was detrusor overactivity during bladder filling in case 1. Another feature of urodynamic finding includes neurogenic change of sphincter EMG in case 1 and decreased bladder sensation in case 2.Urodynamics in our two CJD patients revealed detrusor overactivity and neurogenic sphincter electromyogram, presumably reflecting pathological lesions in the prefrontal cortex/basal ganglia as well as the sacral spinal cord in CJD. |
| Databáze: | OpenAIRE |
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