Serum androgens and prostate-specific antigen levels in androgenetic alopecia: is there a difference between frontal and vertex baldness?
| Autor: | Hubert Arasiewicz, Ligia Brzezińska-Wcisło, Anna Lis-Święty, Irmina Ranosz-Janicka |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty medicine.drug_class Dermatology urologic and male genital diseases behavioral disciplines and activities 030207 dermatology & venereal diseases 03 medical and health sciences Prostate cancer 0302 clinical medicine Antigen Statistical significance Internal medicine Humans Medicine Testosterone Aged business.industry Alopecia Dihydrotestosterone Middle Aged Prostate-Specific Antigen Androgen medicine.disease Vertex (anatomy) body regions Prostate-specific antigen Infectious Diseases medicine.anatomical_structure Endocrinology 030220 oncology & carcinogenesis business Biomarkers medicine.drug |
| Zdroj: | Journal of the European Academy of Dermatology and Venereology. 32:1815-1818 |
| ISSN: | 0926-9959 |
| Popis: | BACKGROUND Androgenetic alopecia (AGA) seems to be a marker of increased risk of prostate cancer (PCa). OBJECTIVE We sought to investigate potential pathophysiological differences between frontal and vertex balding that might have the impact on the incidence of PCa. METHODS Serum concentrations of testosterone (T), dihydrotestosterone (DHT) and prostate-specific antigen (PSA) were measured in 88 subjects with AGA. RESULTS We have examined sixty patients with frontal baldness and 28 patients with vertex baldness. The subgroups did not differ significantly in age, BMI and as regards age of AGA onset, duration of AGA and comorbidities. The mean value of DHT in serum of the men with vertex baldness was higher than those in the men with frontal baldness with statistical significance (P |
| Databáze: | OpenAIRE |
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