The Effects of an Exercise and Lifestyle Intervention Program on Cardiovascular, Metabolic Factors and Cognitive Performance in Middle-Aged Adults with Type II Diabetes: A Pilot Study
| Autor: | Paul Oh, Carol E. Greenwood, Sabrina Scarcello, Susan Marzolini, Alexandra J. Fiocco, Alan Chan, Guy Proulx |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male Gerontology Endocrinology Diabetes and Metabolism Blood Pressure Pilot Projects Context (language use) 030204 cardiovascular system & hematology 03 medical and health sciences Cognition 0302 clinical medicine Endocrinology Heart Rate Preventive Health Services Internal Medicine medicine Humans Dementia Effects of sleep deprivation on cognitive performance Cognitive decline Exercise Life Style Cardiovascular fitness Aged Psychological Tests California Verbal Learning Test business.industry General Medicine Middle Aged medicine.disease 3. Good health Cognitive test Diabetes Mellitus Type 2 Hypertension Female sense organs business 030217 neurology & neurosurgery |
| Zdroj: | Canadian Journal of Diabetes. 37:214-219 |
| ISSN: | 1499-2671 |
| DOI: | 10.1016/j.jcjd.2013.03.369 |
| Popis: | Canada is experiencing a rise in type II diabetes mellitus (T2DM), a known risk factor for accelerated cognitive decline and dementia. Within the context of an aging population, this will impose significant individual and societal burden, making the development of prevention programs imperative.This pilot study examines the effects of the Diabetes Exercise and Healthy Lifestyle Service, a 24-week intervention program, on cardiovascular, metabolic regulation and cognitive function in adults with T2DM.Seventeen middle-aged participants provided blood samples for biological markers, underwent cognitive testing and a physical stress test pre- and post-intervention. Cognitive performance was evaluated using the California Verbal Learning Test (CVLT), Digit Symbol Substitution Tasl (DSST) and fluency test.Adjusted models reveal participants displayed increased cardiovascular fitness (VO2 peak: Mchange=4.09 mL∙kg∙min(-1) SE=1.4), peak heart rate (Mchange= 9.28 beats⋅min(-1) SE=2.68) and change in heart rate (Mchange=10.71 SE=1.76) in response to the stress test (ps0.05) following the 24-week intervention. A decrease in body mass index (BMI) (Mchange= -1.03 SE=0.40) and depressive symptomatology (CES-D: Mchange = -3.62 SE=1.44) was also found (ps0.05). No change was found for lipid and glucose levels. Surprisingly, analyses showed that cognitive performance on the CVLT immediate recall (M= -4.37 SE=2.21), CVTL short-delay recall (M= -1.06 SE=0.55), DSST (Mchange= -3 SE=0.53) and category fluency (Mchange= -1.69 SE=0.78) declined following the intervention (ps0.05); however, decline on the CVLT was limited to adults with co-morbid T2DM and hypertension.Additional research is needed to evaluate the benefit of an exercise and lifestyle program that targets cognitive health in those with T2DM. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect