Choroid plexus, brain and kidney Na+, K+-ATPase: Comparative activities in fetal, newborn and young adult rabbits
| Autor: | J.B. Pritchard, J.R. Pick, L.A. O'Tuama, W. Mitchell, C.S. Kim |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Aging
medicine.medical_specialty ATPase Biology Kidney Blood–brain barrier Fetus Pregnancy Internal medicine medicine Animals Na+/K+-ATPase Young adult General Neuroscience Sodium Brain Anatomy medicine.anatomical_structure Endocrinology Animals Newborn Blood-Brain Barrier Choroid Plexus biology.protein Female Choroid plexus Rabbits Sodium-Potassium-Exchanging ATPase |
| Zdroj: | Neuroscience Letters. 31:37-40 |
| ISSN: | 0304-3940 |
| DOI: | 10.1016/0304-3940(82)90050-7 |
| Popis: | We have studied maturation of brain barrier systems in fetal, newborn, juvenile and adult rabbits. We have compared choroid plexus and brain Na + , K + -ATPase levels in eacc age group, as well as serum and CSF Na + concentration as a measure of the ability of the choroid plexus to generate a gradient from blood to CSF. The choroid plexus appears functionally mature at all ages studied, both in ability to produce a Na + gradient and in ATPase levels. In contrast, brain ATPase levels rose markedly with age. Kidney ATPase measured for comparison showed a pattern similar to brain. |
| Databáze: | OpenAIRE |
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