An overview of fractional anisotropy as a reliable quantitative measurement for the corticospinal tract (CST) integrity in correlation with a Fugl-Meyer assessment in stroke rehabilitation
Autor: | Che Mohd Nasril Che Mohd Nassir, Muzaimi Mustapha, Christina Rowbin, Muhammad Hafiz Hanafi, Mohd Shafie Abdullah, Younis M. S. Firwana, Hasnettty Zuria Mohamed Hatta, Mohd Khairul Izamil Zolkefley |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
030506 rehabilitation
medicine.medical_specialty medicine.medical_treatment Physical Therapy Sports Therapy and Rehabilitation Context (language use) Review Article Correlation 03 medical and health sciences 0302 clinical medicine Physical medicine and rehabilitation Fractional anisotropy Medicine Stroke Rehabilitation business.industry Fugl meyer 030229 sport sciences medicine.disease Corticospinal tract 0305 other medical science business human activities Diffusion MRI |
Zdroj: | Journal of Physical Therapy Science |
ISSN: | 2187-5626 0915-5287 |
Popis: | [Purpose] Understanding the essential mechanisms in post-stroke recovery not only provides important basic insights into brain function and plasticity but can also guide the development of new therapeutic approaches for stroke patients. This review aims to give an overview of how various variables of Magnetic Resonance-Diffusion Tensor Imaging (MR-DTI) metrics of fractional anisotropy (FA) can be used as a reliable quantitative measurement and indicator of corticospinal tract (CST) changes, particularly in relation to functional motor outcome correlation with a Fugl-Meyer assessment in stroke rehabilitation. [Methods] PubMed electronic database was searched for the relevant literature, using key words of diffusion tensor imaging (dti), corticospinal tract, and stroke. [Results] We reviewed the role of FA in monitoring CST remodeling and its role of predicting motor recovery after stroke. We also discussed the mechanism of CST remodeling and its modulation from the value of FA and FMA-UE. [Conclusion] Heterogeneity of post-stroke brain disorganization and motor impairment is a recognized challenge in the development of accurate indicators of CST integrity. DTI-based FA measurements offer a reliable and evidence-based indicator for CST integrity that would aid in predicting motor recovery within the context of stroke rehabilitation. |
Databáze: | OpenAIRE |
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