Feasibility study of immediate pharyngeal cooling initiation in cardiac arrest patients after arrival at the emergency room
| Autor: | Naoki Morimoto, Tetsuya Sakamoto, Hitoshi Kobata, Osamu Nagano, Seishi I, Mitsuru Honda, Hiroshi Hashimoto, Kosaku Kinoshita, Yoshimasa Takeda, Jun Onda, Tomoharu Yokoyama, Masami Ishikawa, Yoshihito Ujike, Kiyoshi Morita, Hiroshi Katayama, Daikai Sadamitsu, Hidekazu Tsuji, Kiyoshi Ichihara, Satoshi Fujimi, Takahisa Kawashima, Hisashi Isobe, Hiroshi Nakano, Masahiro Harada, Takashi Yorifuji, Masanobu Kishikawa, Kazuya Kiyota, Shigeto Oda, Michio Kitaura |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Resuscitation Time Factors Adolescent Brain ischaemia Emergency Nursing Return of spontaneous circulation Body Temperature Young Adult Patient Admission Standard care Hypothermia Induced Maximum difference medicine Humans Therapeutic hypothermia Aged Retrospective Studies Aged 80 and over business.industry Pharynx Rearrest Equipment Design Hypothermia Middle Aged Cardiac arrest Cardiopulmonary Resuscitation Heart Arrest medicine.anatomical_structure Treatment Outcome Anesthesia Selective cooling Emergency Cuff Emergency Medicine Feasibility Studies Intra-arrest cooling Female medicine.symptom Cardiology and Cardiovascular Medicine business Emergency Service Hospital Follow-Up Studies |
| Zdroj: | Resuscitation. 85(12):1647-1653 |
| ISSN: | 0300-9572 |
| Popis: | AIM: Cooling the pharynx and upper oesophagus would be more advantageous for rapid induction of therapeutic hypothermia since the carotid arteries run in their vicinity. The aim of this study was to determine the effects of pharyngeal cooling on brain temperature and the safety and feasibility for patients under resuscitation. METHODS: Witnessed non-traumatic cardiac arrest patients (n=108) were randomized to receive standard care with (n=53) or without pharyngeal cooling (n=55). In the emergency room, pharyngeal cooling was initiated before or shortly after return of spontaneous circulation by perfusing physiological saline (5 °C) into a pharyngeal cuff for 120 min. RESULTS: There was a significant decrease in tympanic temperature at 40 min after arrival (P=0.02) with a maximum difference between the groups at 120 min (32.9 ± 1.2°C, pharyngeal cooling group vs. 34.1 ± 1.3°C, control group; P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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